
Figure 5.
Genome-wide analysis of bone as component measures. Genome-wide association plots for vertebral bone volume fraction (top, N = 472), trabecular plate number density (middle, N = 472), and mechanical strength (bottom; ultimate load to failure, N = 451). (Horizontal dashed line) The genome-wide significance level of P < 0.05. (Crossed symbols) The individual loci reaching significance; (triangles) the regional maxima for each measure.











