Figure 1.
The mouse synthetic population. Each half of a mouse symbol represents one homolog of a chromosome pair. The four founder mice (top row) are inbred strains and are homozygous for all chromosome pairs. The parental mice (second row) are F1 hybrids of the founder strains and are heterozygous for every chromosome pair. The progeny of the [F1 × F1] mating are the genetic equivalent of full siblings and are the studied synthetic population. All synthetic population animals are genotyped across the genome at loci that distinguish the BALB/cJ vs. C57BL/6J alleles (maternal-informative loci) or C3H/HeJ vs. DBA/2J alleles (paternal-informative loci).
