Mutation mapping and identification by whole-genome sequencing

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Figure 6.
Figure 6.

Application to ENU-induced mouse mutant. (A) Homozygosity scoring reveals a single peak on chromosome 2. (B) Log likelihood analysis highlights a 5.5-Mb interval harboring a single nonsynonymous change in the candidate gene Lrp2.

This Article

  1. Published in Advance May 3, 2012, doi: 10.1101/gr.135541.111 Genome Res. 22: 1541-1548

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