Figure 1.
Overview of MBD sequencing results. (A) Schematic representation of hematopoiesis highlighting the three cell types enriched for methylation analysis. HSC and CMP cell populations were lineage depleted (Lin−) and then positively selected with the cell surface markers Sca1 and c-kit. Erythroblast cells were positively selected with antibodies for Ter119 and CD71. (B) Total number of methylation peaks called in each of the three cell populations. (C) Total methylation peak count per chromosome for each cell population: HSC (blue); CMP (orange); ERY (red).
