
Relationship between methylation discordance to location within CpG islands, shores, and shelves. Median within-pair methylation discordance is plotted as box-and-whisker plots against probes depending on location in relation to CpG islands. Data are plotted for CpG islands, CpG island shores (0–2 kb from islands), CpG island shelves (2–4 kb from islands), and “open sea” probes (>4 kb from CpG islands).











