Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

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Figure 1.
Figure 1.

Relationship between within-pair methylation discordance/correlation, zygosity, and chorionicity. Box-and-whisker plots of within-pair methylation discordance (Euclidean distance) and Pearson's correlation coefficient of mean-corrected values in HUVECs, CBMCs, and placenta from MZ and DZ twins, same-sex unrelated (UR) individuals, and MC and DC MZ twins. Numbers of pairs within each category are shown above each graph.

This Article

  1. Published in Advance July 16, 2012, doi: 10.1101/gr.136598.111 Genome Res. 22: 1395-1406

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