Genes predicted to function in nervous system development (NSD). Gene expression (A), regulators (B), and ImaGO tissue annotation (C) for correctly recovered (known) and newly predicted NSD genes. The two expression clusters comprising the majority of the predicted NSD genes are shown. The two clusters are driven by different, but largely overlapping, sets of regulators. Within each of the two clusters, the newly predicted NSD genes show similar expression profiles and similar sets of regulators to those of the recovered, known NSD genes. Moreover, both the recovered and the newly predicted NSD genes show similar expression patterns in nervous system tissues, which were not used as input features.
