Multiple Uhg-family members oscillate with peak expression during the light phase. (A) Fold-changes of median-normalized expression levels of Uhg-family members are shown as a heatmap. (White and black bars) The LD regimen under which these samples were collected. The order of transcripts along the vertical axis is identical between wild-type and per0. Note that in per0 brains, peak Uhg expression is phase-delayed by ∼6 h. (B) The fold-changes of all snoRNAs and snmRNAs encoded by Uhg genes and expressed at a detectable level are median-normalized and displayed as a heatmap. (C) Expression levels of all cycling Uhg-family members in DD are damped relative to the light phase of LD. The light phase is defined as ZT0 and ZT6 for LD samples, and CT0, CT4, and CT8 for DD samples. (Error bars) Mean ± standard error of the mean.
