Impact of microRNA regulation on variation in human gene expression

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Figure 5.
Figure 5.

Genes that are differentially expressed or under stabilizing selection during primate evolution are significantly enriched in miRNA target genes. (A) The genes that are differentially expressed between human and chimpanzee (deHC). (B) The genes that are differentially expressed between human and macaque (deHR). (C) The genes that are under stabilizing selection. All of the 20,689 Ensembl genes sequenced by Blekhman et al. (2010) are used in A, B, and C. (D) The combinational miRNA target gene determination methods. Only the 16,772 protein-coding genes examined in Blekhman et al. (2010) are used.

This Article

  1. Genome Res. 22: 1243-1254

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