Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts

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Figure 1.
Figure 1.

Expression levels of genes and chimeric transcripts in humans. The expression of genes in human tissues ranges from 0.001 to 15,700 RPKM, with a median of 0.588, whereas the expression of chimeras ranges from 0.006 to 17.8 RPKM with a median of 0.02. Most of the genes involved in the formation of chimeras are moderately to highly expressed, as their expression ranges from 0 to 2495 RPKM, with a median of 12.6. The trend is also observed for the translated chimeras and their parental genes (Wilcoxon test, P-value < 5 × 10−6). The whiskers of the boxplot extend to the data extremes (see also Supplemental Fig. S4).

This Article

  1. Genome Res. 22: 1231-1242

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