Figure 6.
Chromatin structure around the 5′ end of genes evolutionarily conserved across major eukaryotes. The data of genome-wide nucleosome positions in vivo were curated from the literature and the composite distributions of nucleosome locations were shown for each species in the right panel, aligned by the TSS. The life tree was adapted from the kingdom-level phylogenetic tree of eukaryotes (Baldauf et al. 2000) and simplified in the figure. (Red circle) Those having a substantial portion of the nucleosome over the TSS; (blue circle) those where the TSS is located in the NFR. See Supplemental Table S2A for consensus positions.
