The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2

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Figure 7.
Figure 7.

Phylogenetic analysis. Sequences shared among distinct subterminal genomic loci in chimpanzee (blue) and gorilla (red) were aligned to human (NCBI build35) and orangutan (ponAbe2) orthologous sequences (see text for details). Neighbor-joining phylogenetic trees (bootstrap values at each node) were constructed from four different genomic regions (A–D). Only the chromosome 10 segment (A) is shared between gorilla and chimpanzee cap sequences. We estimate the evolutionary time (green dots = mya) of duplications and expansions assuming a human-orangutan divergence of 14 mya.

This Article

  1. Genome Res. 22: 1036-1049

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