Duplication and fosmid probe map. The pattern of segmental duplications is shown for (A) a 463-kbp region of human chromosome 2 (chr2:113840263-114303469) and (B) a 341-kbp region mapping to chromosome 10 (chr10:19359773-19700390) based on human genome annotation (NCBI build35). Computationally predicted human, chimpanzee, and gorilla duplications (red = excess depth-of-coverage of aligned whole-genome shotgun sequence) as well as a heat map indicating the copy number are displayed. Fosmid clone contigs are reported below each genomic region. Human fosmid probes underlying each region are shown and grouped (2A–E and 10A–D) based on the pattern of hybridization to chimpanzee and gorilla subtelomeric cap and subcap regions. (HSA) Homo sapiens, (PTR) Pan troglodytes, (GGO) Gorilla gorilla.
