Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals

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Figure 3.
Figure 3.

Representative data of mRNA stabilities. Relative levels of mRNA remaining were determined by BRIC-seq. The relative quantitative values at time 0 h were arbitrarily adjusted to 100%. (A) GO categories associated with regulatory functions. (Left) ATF1 is involved in transcription factor activity; (center) PLXNC1 is involved in multicellular organismal development; and (right) GPR157 is involved in G-protein-coupled receptor protein signaling pathway. (B) GO categories associated with housekeeping functions. (Left) SNRPB is involved with the spliceosome; (center) TIMM17B is involved with the mitochondrion; and (right) EIF3F is involved in translation.

This Article

  1. Genome Res. 22: 947-956

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