Figure 1.
Age-related gene expression change in the PFC and CBC. (A) Age distribution of samples used in this study. Each point represents an individual, with technical replicates shown as a second point below the first. Only one of the two replicates was used in the main analysis. The colors indicate brain regions (red, PFC; gray, CBC). The x-axis represents individual age in fourth root (age1/4) scale. Numbers of age-related genes (B) and genes with species-specific expression profiles (C) identified in the PFC (red) or CBC (gray). The red arrows highlight excess human-specific expression changes in the PFC.
