DNA methylation fingerprint in non-tumoral human diseases. (A) Unsupervised hierarchical clustering and heatmap of several non-tumoral diseases showing distinct DNA methylation profiles. (B) Unsupervised hierarchical clustering and heatmap showing significant differences between the DNA methylation patterns of dementia with Lewy bodies and normal controls. The CpG methylation platform used was unable to detect significant differences in the case of Alzheimer's versus healthy brain tissues. (C) Unsupervised hierarchical clustering and heatmap showing differences between dementia with Lewy bodies and neuroectodermal tumors (glioma and neuroblastoma).
