Whole genome sequencing of matched primary and metastatic acral melanomas

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Figure 2.
Figure 2.

Somatic SNVs analysis in acral melanoma samples. (A) Somatic SNV mutation rates of all SNVs and C>T/G>A transitions for expressed genes in the primary (P-EXP) and metastatic tumors (M-EXP) and nonexpressed genes (P-NON and M-NON). (B) Proportion of somatic SNVs by class in the primary and metastatic tumors for the whole genome (WG) and coding regions (CDS). (C) Frequency of bases ±5 bp of whole genome C>T/G>A transitions in the primary tumors. (D) Frequency of bases ±5 bp of whole genome C>T/G>A transitions in the metastatic tumors.

This Article

  1. Published in Advance December 19, 2011, doi: 10.1101/gr.125591.111 Genome Res. 22: 196-207

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