Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting

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Figure 3.
Figure 3.

Codon usage and functional classification of neural network-defined TISs: (A) Distribution of the number of putative TISs per transcript. (B) Functional classification of putative TISs. (C) TIC usage in putative TISs, either including AUG (upper row) or for near-cognate codons only (bottom row). (D) Average codon frequency over all three reading frames in the analyzed 5′ UTRs, considering either all possible codons (left), the 10 TIS-relevant codons identified in our study only (middle), or near-cognate codons only (right).

This Article

  1. Published in Advance August 9, 2012, doi: 10.1101/gr.139568.112 Genome Res. 22: 2208-2218

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