
Simplified models for the role of BEAF-32 during evolution of Drosophila species. (A) Two alternative possibilities explaining how alterations in BEAF-32 binding may affect transcription. Blocks indicate genes. (Black and white) Different transcription regulatory modes of the genes. (Gray) Converged regulation for the two genes. Gain or loss of BEAF-32 binding when gene pairs are reorganized to maintain proper transcription (top). Gain or loss of BEAF-32 binding when gene organization does not change to create transcription diversity (bottom). (B) Phylogeny and phenotype of Drosophila species analyzed in this study.











