Natural genetic variation in yeast longevity

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Figure 2.
Figure 2.

Genomic regions of QTL 1 and QTL 5. (A) QTL 1 is located on chromosome IV (bp 370,000–387,742). It contains 12 genes within a region of 18 kbp; one of them is SIR2. (B) QTL 5 is located on chromosome XII (bp 446,389–487,500). It contains 23 protein-coding genes, one tRNA gene, some ARS consensus sequences, and the rDNA cluster (RDN1). Two copies of the rDNA are shown here, but the rDNA cluster contains between 100 and 200 repeats. The x-axes are in kilobase pairs. (Large dark dots) Centromeres; (vertical dashed lines) QTL boundaries. The diagrams were adapted from the Saccharomyces Genome Database (www.yeastgenome.org) (Cherry et al. 1997).

This Article

  1. Genome Res. 22: 1963-1973

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