Aberrant firing of replication origins potentially explains intragenic nonrecurrent rearrangements within genes, including the human DMD gene

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

The presence of microhomologies at breakpoint junctions. The graphs represent the extent of microhomologies at the deletion breakpoint junction sequences in DMD (A) and other genes (B). The x-axis represents the number of bases homologous in both junction sequences of a deletion. The y-axis represents the number of samples that have been observed to have the indicated microhomology.

This Article

  1. Genome Res. 22: 25-34

Preprint Server