Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

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Figure 3.
Figure 3.

Validation of predicted A-to-I editing events identified via RNA-seq. (A) Scatterplot of editing ratios for the full set of 93 A-to-I editing events identified by RNA-seq and the traditional clonal sequencing method (20 clones were picked for each editing site). Pearson correlation coefficient is shown. Data points corresponding to false-positive or false-negative predictions are shown as green dots. (B) Same as A, but for the 29 editing events in the CTSB gene (read coverage, 35–69 reads per site). A total of 50 clones were picked for each site.

This Article

  1. Genome Res. 22: 142-150

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