Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions

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Figure 3.
Figure 3.

H3K9me3 can distinguish poised from active and intermediate enhancers. (A) Heatmap of CHD7-bound enhancers showing cluster analysis with H3K9me3. Subclass designations from Figure 1D were used to classify each H3K9me3-clustered enhancer class. (B) Aggregate plots of CHD7, H3K4me1, H3K27ac, and H3K9me3 at each enhancer class following H3K9me3 clustering. (C) Percentage of enhancers in each class after H3K9me3 clustering that overlapped with enhancers in the corresponding class after H3K27me3 clustering.

This Article

  1. Genome Res. 21: 1273-1283

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