Figure 1.
Reconstructions of the genomes of representative CC lines IL-18 and IL-507 from the hidden Markov model (HMM) implemented by HAPPY. The x-axis shows the 19 autosomes. Each reconstruction is represented by two panels. The top panel y-axis shows the eight CC founders, and the probability of descent from a founder at a locus is represented by the shade of gray, with white = 0 and black = 1. Regions where a single haplotype predominates appear as dark horizontal bands; loci with residual heterozygosity or where the founder haplotypes are indistinguishable are gray. The lower panel indicates local heterozygosity (red).
