Genetic analysis of complex traits in the emerging Collaborative Cross

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Figure 4.
Figure 4.

Baseline body weight genome scan. (A) Eight-allele model (black) indicates a QTL on Chr 4, named here Bwq14, and several suggestive peaks. No peaks reach significance using the marker-based method (light gray). (B) Allele effects plot for Bwq14 suggest a shared NZO/HlLtJ and C57BL/6J allele at this locus is associated with an increase in body weight (dark-gray and light-blue lines). The color corresponding to each founder strain is the same as in Figure 1D. (C) A region of sequence identity between NZO/HlLtJ and C57BL/6J (black bars) reduces the candidate region to 4.69 Mb.

This Article

  1. Genome Res. 21: 1213-1222

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