Extensive relationship between antisense transcription and alternative splicing in the human genome

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

SAS genes tend to have concordant expression and antisense-correlated splicing events. (A) The majority of SAS gene pairs have positively correlated gene expression values across the 176 LCL samples. (B,C) Individual probesets in known (B) and novel (C) SAS genes, have either positive or negative correlations (x-axis) between their SI values and the expression of the antisense gene or construct (the y-axis is the Bonferroni-corrected P-values of Spearman correlations).

This Article

  1. Genome Res. 21: 1203-1212

Preprint Server