Differential expression using HeliScopeCAGE. (A) Comparison between HeliScopeCAGE and microarray. (i) the number of genes detected in both of THP-1 and HeLa RNA with each platform (detected all of the three technical replicates). (ii) The number of genes detected as differentially expressed. False discovery rate (FDR) <0.001 for HeliScopeCAGE and Bstatistics >0 are used as criteria for the differential expression. (B) Genomic view of a novel Human Endogenous retrovirus (HERV) related transcript highly expressed in THP-1 but not detected in HeLa. (i) and (ii) On linear scale; (iii) and (iv) log scale for HeLa and THP-1, respectively. (Green) Plus strand; (purple) minus strand relative to genome assembly.
