Genome-wide identification of conserved regulatory function in diverged sequences

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Figure 3.
Figure 3.

Overview of the detection of covert regulatory elements. We look for functional orthologs of conserved human/frog CNEs in the zebrafish sequence by computing alignments for syntenic and control loci and using a SVM to distinguish significant from random alignments.

This Article

  1. Published in Advance May 31, 2011, doi: 10.1101/gr.119016.110 Genome Res. 21: 1139-1149

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