Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

SLC35B4 regulates gluconeogenesis. Slc35b4 mRNA levels (A,C) and glucose synthesis (B,D) were measured following transfection of H2.35 mouse liver-derived cells (A,B) or human hepatoma-derived HepG2 cells (C,D), with either a nontargeting siRNA (control) or an siRNA targeting Slc35b4. Levels of mRNA and glucose synthesis were measured 48 h post transfection. Data are presented as mean ± SEM. *P < 0.05 relative to control siRNA.

This Article

  1. Published in Advance April 19, 2011, doi: 10.1101/gr.120741.111 Genome Res. 21: 1065-1073

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research