Figure 1.
The first transcriptional map of the human MHC: Haplotype-specific pattern of expression. Each cell line transcription level against the minimal level of the three cell lines is displayed; (pink) PGF, (orange) COX, and (purple) QBL. Bars corresponding to genes on the minus strand are displayed leftward and those for the plus strand rightward. Boxes in the class III and class II regions indicate haplotype-specific segmental duplications. Overall, the MHC class II region presents the highest minimal expression (dark blue). The most differentially expressed gene is ZFP57, located at the beginning of the class I region.
