Cartoon demonstration of the adaptive procedure for an increase in bandwidth Hb. (A) When the band is 2, then the largest contribution to mean-shift vector calculations, e.g., for the cyan bin, comes from two neighboring bins. Following the partitioning, two bins within one segment get “frozen,” and bins within it are excluded from partitioning on the next step. New partitioning allows for freezing of more bins that are skipped at the next step when bandwidth equals 4. (B) The deletion region is clearly seen by the eye but could not be detected as a whole at a bandwidth of 2. Only a small portion is detected as CNV and gets “frozen.” After new partitioning with a bandwidth of 3, the region is not frozen anymore and is included for partitioning on the next step (bandwidth of 4), where the complete region of deletion is detected.
