Low-coverage sequencing: Implications for design of complex trait association studies

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Figure 3.
Figure 3.

Genotype concordance and fraction of genotypes by non-ancestral allele counts (60 individuals sequenced at 4×). Genotype concordance (y-axis on left, dots) and fraction of genotypes (y-axis on right, bars) for simulated data, broken down by genotype category (homozygotes for the ancestral allele [HomRef], heterozygotes [Het], and homozygotes for the non-ancestral allele [HomAlt]) are plotted as a function of non-ancestral allele count among 60 individuals sequenced at 4× (x-axis).

This Article

  1. Published in Advance April 1, 2011, doi: 10.1101/gr.117259.110 Genome Res. 21: 940-951

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