High sensitivity to aligner and high rate of false positives in the estimates of positive selection in the 12 Drosophila genomes

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Figure 1.
Figure 1.

Impact of aligner choice on the estimated rates of protein evolution. (A) Box plot of ω, or dn/ds,Ka/Ks, values per gene depending on the aligner used. (B) Frequency distribution of the difference per gene between ω based on a given aligner and the average ω among all five aligners. (C) ω of AMAP vs. T-Coffee.

This Article

  1. Published in Advance March 10, 2011, doi: 10.1101/gr.115949.110 Genome Res. 21: 863-874

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