Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing, and “resurrected” pseudogenes in the mouse genome

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Figure 3.
Figure 3.

(A) Cumulative gene identification rate as a function of the number of potential identifiable (hypothetical) peptides per protein-coding gene. (B) As before, but analysis for protein-coding exons. Note that considered peptides were fully tryptic, ranged from eight to 30 residues and were unique to a genomic locus. (C) Inverse cumulative validation rate of all protein-coding genes as a function of the number of peptides identified per gene. (D) As before, but for protein-coding exons.

This Article

  1. Genome Res. 21: 756-767

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