RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

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Figure 2.
Figure 2.

Categories of simple RAF gene fusion breakpoints. Fusion sequences aligned with KIAA1549 (green) and BRAF (yellow). (Blue) Nucleotides that align to neither reference gene (insertions); (red) nucleotides that align to both reference genes (microhomology). (A) Seamless transition with defined breakpoint. (B) Insertion. (C) Breakpoint microhomology. (D) Flanking microhomology only.

This Article

  1. Published in Advance March 10, 2011, doi: 10.1101/gr.115782.110 Genome Res. 21: 505-514

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