Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons

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Figure 2.
Figure 2.

Comparison of chimera detection sensitivity among methods. (A) Chimera detection sensitivity as a function of chimera divergence; (B) chimera detection sensitivity according to the shared level of taxonomy between the proposed parental sequences. Cumulative false-positive rates were as follows: CS, 1.6%; WigeoN, 0.67%; BellerophonGG, 7.13%; KmerGenus, 0%.

This Article

  1. Published in Advance January 6, 2011, doi: 10.1101/gr.112730.110 Genome Res. 21: 494-504

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