Adaptive seeds tame genomic sequence comparison

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

LASTZ and BLASTN use fixed-length seeds and present similar performance to LAST with fixed-length seeds. (Circles) LAST adaptive seeds; (crosses) LAST fixed-length seeds. (A) P. yoelii contigs are aligned to P. falciparum chromosomes using the same score matrix as in Figure 3C. Triangles show performance of LASTZ executed with corresponding parameters for different LASTZ-seed lengths. (B) A simpler match/mismatch scoring scheme is used. Squares present the performance of BLASTN and the numbers correspond to BLASTN-seed lengths.

This Article

  1. Genome Res. 21: 487-493

Preprint Server