Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1–S6K pathway signaling

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

(A,B) Validation and functional characterization of TORC1–S6K pathway regulators confirmed in the secondary screen (clusters 1 and 2). S6_S2R+ cells were incubated with dsRNAs targeting the indicated genes, and lysates were analyzed by Western blotting. See also Supplemental Table S2 for results and analysis related to the secondary screens and subsequent follow-up experiments.

This Article

  1. Published in Advance January 14, 2011, doi: 10.1101/gr.111492.110 Genome Res. 21: 433-446

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research