Figure 3.
The HC interaction network. Visual representation of the relationships between AD seeds and HC interactors. Seeds are depicted in pale orange whereas HC matrix and library interactors are colored in dark and light blue, respectively. The AD dysregulated interactors are highlighted in red (up-regulated) and green (down-regulated). Dark violet lines denote those interactions confirmed by pull-down and coimmunoprecipitation experiments, whereas lilac lines represent interactions confirmed only by coimmunoprecipitation. Candidate–candidate interactions are removed for clarity.
