Figure 10.
RNA editing in Drosophila small RNAs. We collected S2 and head small RNA reads with one or two mismatches to 3′ cis-NATs or miRNAs and tabulated the nature of their nucleotide changes. (A) Endo-siRNAs from 3′ cis-NATs exhibit a preponderance of A→G changes indicative of adenosine deamination. (B) In contrast, miRNA reads do not collectively exhibit enrichment for A→G changes. (C) miR-100 is a highly conserved miRNA with abundant A→G transition reads present in multiple libraries. The full analysis is presented in Supplemental Table S8.
