A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

Quantification of glutamate levels in cortical extracts and GABA levels in cerebellar extracts of Fmr1-KO brain vs. WT. Glutamate cortical (A) and GABA cerebellar concentrations (B) are significantly reduced in Fmr1-KO extracts compared to WT (P = 0.011; P = 0.038, respectively; n = 9 for each genotype).

This Article

  1. Genome Res. 21: 2190-2202

Preprint Server