Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

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Figure 5.
Figure 5.

The genomic distribution of multicopy arrays across the chromosomes of Leishmania species. The multicopy genes are colored by number of copies: (white) 2, (yellow) 3, (orange) 4, and (red) >4. Chromosomes with the normal somy for that species are shown in black; for L. major, L. infantum, and L. mexicana, this is disomy, and for L. braziliensis, this is trisomy. (Red) The supernumerary chromosomes. The chromosomes are shown to scale; however, arrays are shown relative to the center point of the array, but are not to scale. (A) L. braziliensis M2904 (231); (B) L. major Friedlin (207); (C) L. mexicana U1103 (134); (D) L. infantum JPCM5 (216). The total number of multicopy genes for each species is shown in brackets.

This Article

  1. Genome Res. 21: 2129-2142

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