
Application of EDGE to mouse tissues. (A) Using a Poisson log linear model, 327 and 945 genes were identified as differentially expressed between Mc1r+/+ and Mc1re/e in (A) neonate dermis (FDR < 5%) and (B) spleen (FDR < 0.1%), respectively. Average gene counts from wild-type (five libraries each for neonate dermis and spleen) and mutant (six for neonate dermis and five for spleen) EDGE libraries are plotted against each other on a log10 scale. Differentially expressed genes are plotted in red. (C) EDGE tags were detected for 17,535 unique mouse genes in at least one tissue, and 1589 genes were expressed in only a single tissue.











