Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant

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Figure 2.
Figure 2.

Additional PTES products identified from RT-PCR amplicons. Amplification products from the C19orf2 E10-E3 and HDGFRP3 E5-E2 RT-PCR validation are shown. Structures, genomic splice junctions, and associated cDNA sequence traces are shown. Splice junctions are indicated using dotted lines in both DNA and cDNA sequences. Terminal gt-ag dinucleotides of inferred introns within genomic sequence are shown in red. Sequence internal to RefSeq exons is shown in upper case. (E) Exonic; (I) intronic; and (3′) novel exonic sequence derived from 3′ of the annotated C19orf2 gene.

This Article

  1. Genome Res. 21: 1788-1799

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