Linkage to human homologs and summary of expression and phenotype. The human orthologs of the mouse GT genes are aligned to their cytoband on an ideogram of the human X chromosome. Also shown are the names of human and mouse homologs and a brief summary of the observed expression pattern of the beta-galactosidase reporter gene in the embryos. (Bold mouse genes) Gene names for GT lines that gave a phenotype. Eleven mouse genes were tested by two or more GT lines and are indicated in parentheses next to the mouse gene name as a ratio of lines with similar expression or phenotype. The phenotype for the gene Nono was confirmed by inverting the GT and restoring Nono expression and normal phenotype in aggregated embryos (#). (Bold human genes) Names associated with human disease or syndromes when mutated.
