Figure 6.
Site modality is independent of motif presence or score. (A) Box-whisker plots of bimodal, monomodal, or low FOXA2, PDX1, or HNF4A peak heights. Statistical significance between groups was detected using a Kruskall-Wallis non-parametric test with a Dunn's post-test, with a P < 0.05 threshold. (***) P < 0.001. (B) Fraction of peaks in the bimodal, monomodal, or low site classes in the FOXA2 (islet and liver), PDX1, HNF4A peak sets that contain a high-scoring binding motif. (C) Frequency distribution of PWM scores for the three site classes for each TF peak set.
