The mutational spectrum of non-CpG DNA varies with CpG content

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Figure 2.
Figure 2.

Percent CpG content and non-CpG mutations as a function of L1 family age. The percent CpG content and non-CpG mutations were determined as described in the Methods. The relationship of CpG content to age is best fit by an exponential decay function (A), but that of the non-CpG mutations is best fit by a sigmoid (logistic) function (B; see text). Numbers indicate L1Pa families.

This Article

  1. Published in Advance May 24, 2010, doi: 10.1101/gr.103283.109 Genome Res. 20: 875-882

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