The mutational spectrum of non-CpG DNA varies with CpG content

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Figure 1.
Figure 1.

Primate L1 families. A full-length generic primate L1 element is shown. The primate-specific L1Pa families examined here are placed on a simplified primate tree according to their average ages (see Methods). The columns give the KB of ORFII orthologs of the various families used for the various analyses in this paper (see Methods). M, P, and H indicate Macaca mulatta (macaque, Old World monkey), Pan troglodytes (chimpanzee), and Homo sapiens (human), respectively. The ages for the divergences of theses species were derived as described earlier (Walser et al. 2008). See Methods and Results, for details on the various steps outlined on the right side of the figure.

This Article

  1. Genome Res. 20: 875-882

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