Figure 4.
Distance dendogram based on the minimum Kullback-Leibler divergences between TF position weight matrices from the Jaspar database and reference matrices of Figure5. Note that the binding profiles generated using the SELEX method are in general similar to existing matrices for the same or related factors in cases where they are available. Note also that the profiles generated using SELEX for 14 of the 23 major DNA-binding domain families occupy most major branches of TF binding specificities, highlighting the broad utility of the method.
