Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

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Figure 5.
Figure 5.

Divergence in TFBSs and intersite sequences within HCTs for 273 PWMs. The sequence divergence in human–chimp comparisons indicates that TFBSs tend to be more conserved than intersite sequences for HCTs of most PWMs (86.4%). For 31 of them (red) the difference is significant (after correction for multiple testing).

This Article

  1. Published in Advance April 2, 2010, doi: 10.1101/gr.104471.109 Genome Res. 20: 565-577

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